Eye drops "Tsiprolet": instructions for use, composition, analogues, indications and contraindications, reviews

• October 17, 2018
• Ophthalmology
• Anatoly Ivanov

In the article we will look at the instructions for use of Tsiprolet eye drops.

The remedy is indicated for a number of visual defects and some diseases. This medicine is a broad-spectrum drug; you should consult a doctor before using it.

The best eye drops for eye burns: types and properties

Eyes are the most sensitive human organs to external influences. Any aggressive contact of the delicate eye structures with chemicals, steam, hot objects, fire, ultraviolet radiation leads to severe damage and often to dire consequences. Therefore, it is important to know how to protect the organs of vision and how to provide first aid for various types of eye burns.

Causes and classification

Mostly, the eyes suffer from chemical and thermal burns, since almost all people daily interact with household chemicals, which include various chemicals. Careless handling of plumbing cleaners or laundry detergents can result in chemical burns. And thermal damage can easily occur during careless cooking. Drops of hot oil or fat or steam entering the mucous membrane of the eye cause a thermal burn. Radiation injury is much less common.

Depending on what caused the burn, the following types of lesions are distinguished:

1. Thermal. They develop as a result of exposure to high temperatures due to hot splashes of fat entering the eye during cooking, exposure to steam, sparks from fireworks, etc. The skin of the eyelid, conjunctiva, and cornea are more often injured from thermal effects, and burns to deeper ocular structures are less likely to occur.
2. Chemical. Similar damage is caused by alkalis and acids. Lead to the death of cells that are directly exposed. Among the acids that most often injure people's eyes, they are sulfuric, hydrochloric and acetic acids. They are part of many household chemicals. When affected by acid, the protein in the eye mucosa curls up and prevents the chemical from penetrating into the deeper layers. Alkalies penetrate into the ocular structures, destroy cells and contribute to the development of wet necrosis. They differ in the duration of action of the damaging substance. It gradually penetrates through the superficial tissues from the site of damage to the deeper layers. Among alkalis, burns are most often caused by potassium, magnesium, sodium hydroxide, lime, and ammonia.
3. Radiation. Caused by prolonged or sudden exposure of the eyes to ultraviolet (short-wave) or infrared (long-wave) rays. The damage is called electroophthalmia. Ultraviolet light causes burns to the skin, cornea, and conjunctiva. Long waves easily penetrate the cornea and injure the retina. Ultraviolet burns can occur as a result of abruptly leaving the dark into a brightly lit place or while observing a solar eclipse without appropriate protection. Most often, long-wave rays injure the eyes of people working with welding.

Beneficial properties of the drug and its pharmacological effects

Ciprolet eye drops contain an antibiotic called ciprofloxacin. It is effective in the treatment of ophthalmic pathologies that develop due to the activity of pathogens such as E. coli, staphylococcus, streptococcus, chlamydia, diphtheria bacteria, and so on. After the instillation procedure, this medicine is very quickly absorbed into the blood, while it is just as easily excreted and does not accumulate in the body.

Symptoms

When eye burns occur, tissue cells die, causing blood clots to appear in the capillaries, and plasma leaks into the surrounding tissues.

All types of burn injury are accompanied by similar symptoms:

• swelling of the cornea, conjunctiva;
• severe pain in the eye;
• redness of the skin of the eyelids and eyeball;
• photophobia;
• changes in visual fields;
• lacrimation;
• increase or decrease in eye pressure;
• decreased visual acuity;
• corneal clouding;
• blepharospasm, in which it is difficult to open the eyelids.

Adverse reactions

It is worth paying attention to the side effects of the medication. After instillation of the medicine, the following may be observed:

• itching;
• slight burning sensation;
• conjunctival irritation;
• lacrimation;
• the appearance of a foreign body sensation in the eyes;
• decreased clarity of vision.

In some cases, when using the medicine, a specific taste may occur in the mouth. Some patients complain of nausea after instilling the medicine. If side effects occur, treatment with Tsiprolet should be stopped and medical help should be sought.

First aid

In case of eye burns, it is important to provide first aid to the person as quickly as possible. The preservation of vision often depends on this.

First aid boils down to the following:

• removing residual damaging substances using a sterile cotton swab;
• rinsing the eyes with clean water or saline solution from a large syringe for 15 minutes (if the burn is caused by an alkali, rinsing is carried out with a 2% boric acid solution. When exposed to acids, a soda solution is used for rinsing);
• instillation of a solution of novocaine, lidocaine (4%) or Levomycetin (0.2%). You can use Acetopt, Sofradex. It is better to perform the procedure in a darkened room, as instillation is very painful.

Description and composition of the drug

Ciprofloxacin hydrochloride in terms of ciprofloxacin 3 mg is the active ingredient of Tsiprolet drops.
This is a compound related to fluoroquinolone derivative antibiotics. Sodium chloride 9 mg, hydrochloric acid 0.000034 mg, disodium edetate 0.5 mg, benzalkonium chloride solution 50.0% are auxiliary components.

In order for the drug to maintain its effectiveness for a long time and not deteriorate, the composition includes excipients.

Tsiprolet drops have a light yellow tint. May be colorless or transparent. Available in 5 ml plastic bottles with a convenient dropper. Packed in a cardboard box.

Tsiprolet is a drug with antibacterial properties. The active component of the drug is ciprofloxacin. This substance belongs to the fluoroquinolone family and helps to actively suppress the activity of pathogens such as Klebsiella, staphylococcus, streptococcus, enterobacteria, chlamydia, E. coli, citrobacter, diphtheria corynebacterium, etc.

The auxiliary components of the medicine include:

• Mannitol.
• Acetic acid.
• Sodium acetate.
• Water.
• Benzalkonium chloride.

The medication is available in the form of tablets, injection solution or eye drops.

On the shelves of pharmacies you can also find another form of the drug in question - Tsiprolet A. This drug is available in tablet form. Its difference from the usual Ciprolet lies in the presence of two active components in the tablets: ciprofloxacin and tinidazole.

• When using Tsiprolet drops with antimicrobial agents (antibiotics, aminoglycosides, metronidazole, clindamycin), as a rule, an increase in the therapeutic effect of each drug is observed.
• If the organs of vision are damaged by streptococcal infection, Tsiprolet can be combined with Ceftazidime, Azlocillin and other beta-lactam antibiotics.
• If affected by staphylococcus, drops can be combined with Vancomycin and isoxazolepenicillins. This combination helps to increase the therapeutic effect.
• To combat anaerobic infections, it is possible to combine the drug with Clindamycin or Metronidazole.

Drug groups

Therapeutic measures for all types of burns are quite similar, only the doses and duration of the therapeutic course differ depending on the degree of damage to the eye structures.

The main groups of drugs that are used for burn injuries to the eye are shown in the table.

Drops recommended for different types of burns

For any type of burn, it is important to relieve pain and prevent infection from entering the affected tissue.

For thermal burns

For thermal damage, the following drops can be used:

1. Inocaine. The active substance is benoxynate hydrochloride. Local anesthetic that blocks nerve endings.
2. Visoptician. Eliminate photophobia, itching, burning, lacrimation, swelling.
3. Okomistin. An antiseptic that forms a protective film on injured tissues.
4. Prokulin. Relieves swelling, pain, has a vasoconstrictor effect.

As part of complex therapy for burn damage to the eyes, Emoxipin is prescribed, which helps restore energy metabolism in tissues and accelerates their healing, strengthens blood vessels, restores blood circulation, and stimulates regeneration processes.

For radiation burns

Radiation burns are treated with the following drops:

1. Corticosteroids. Hydrocortisone, Dexamethasone, which help eliminate local swelling.
2. Lidocaine. The solution contains sodium chloride and benzalkonium, lidocaine hydrochloride. Prescribed for eye burns to reduce tissue sensitivity.
3. Derinat. Drops with an immunomodulatory effect. They help quickly regenerate injured areas, preventing the appearance of scars.
4. Phloxal. Drops with antibacterial action. Prevents infection of damaged tissues.
5. Tsiprolet. Antimicrobial drops for a wide range of applications. In case of eye burns, they are instilled 5 times a day, 2 drops into each eye.
6. Levomycetin (active ingredient chloramphenicol) acts against most gram-positive and gram-negative bacteria.

Drops for chemical burns

A 1% solution of Dicaine helps with eye burns of chemical origin.
This is a local anesthetic that contains sodium chloride and leocaine, which reduces the sensitivity of sodium channels through which pain impulses are transmitted. Drops reduce pain and have a local anesthetic effect. Atropine is used. The active ingredient of the drops is atropine sulfate. Helps relieve pain and prevent adhesions.

Ciprofloxacin also helps, which has anti-inflammatory and antibacterial effects.

Analogues of Tsiprolet

• Maxitrol drops
  are a dual-action drug. It actively reduces swelling, eliminates redness syndrome and pain in the affected area, and has an antimicrobial effect. The drug is produced on the basis of three active ingredients (neomycin, dexamethasone, polymexin B), which makes it effective in the fight not only against microorganisms, but also against the original source of infection. Eye drops may have a minor effect on your ability to drive. After use, you must wait until your vision clears. Due to the lack of clinical data, it is not recommended to use Maxitrol during pregnancy and breastfeeding, and in children in the first year of life. Drops are dispensed in pharmacies only with a prescription from the attending physician.
• Tobrex
  is a drug with a combined effect that has an antibacterial and anti-inflammatory effect. The active ingredients are tobramycin and dexamethasone. The drops have no age limit; they can be used by children from birth. During pregnancy and during the lactation period, the use of the product is not recommended. If blurred vision appears after instillation, you must wait until it recovers. Tobrex does not affect the reaction speed, therefore it is allowed to drive vehicles. Dispensing in a pharmacy is only available with a doctor's prescription.
• The medicinal solution " Tsipromed
  " is used for diseases with inflammatory processes in the anterior eye chamber. The composition contains the active ingredient - ciprofloxacin, and other additional components that ensure long-term storage and effectiveness of treatment. During instillation of the drug, minor visual disturbances may occur. You must wait until it is restored, after which you are allowed to drive vehicles. The use of Tsipromed during pregnancy and lactation is not recommended. Children can use the product from the age of 1 year. Dispensing in a pharmacy is carried out only with a prescription from the attending physician.
• Garazon
  is an eye drop used in ophthalmology to treat bacterial infections of the eyes and ears. The drug contains gentamicin and betamethasone. An antibiotic in combination with a hormonal component has an antimicrobial and anti-inflammatory effect. Drops are used to treat diseases of the anterior segment of the eyes. Garazon is not recommended for use during pregnancy and lactation. Clinical data on the safety of use in children under 12 years of age have not been established. You can purchase the drug in a pharmacy only with a doctor's prescription.

Forecast

The prognosis for a person who has received an eye burn will depend on timely treatment. Most superficial burns disappear without a trace. Moderate and severe damage is fraught with scarring of the eyelids, the development of cataracts, and death of the eyeball. Radiation damage affecting the retina often leads to vision loss.

Author of the article: Bakhareva Elena Sergeevna, specialist for the website glazalik.ru Share your experience and opinion in the comments.

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What happens to the eyes during welding and what are the consequences?

Welding is not only the joining of metal parts; it is also used when working with other materials. Electric current is used as a source of formation of the welding arc. So what exactly causes harm?

When welding, rays of three spectra are released at once: infrared, ultraviolet and light. The intensity is too high for the human eye, it exceeds the permissible level.

There is a common expression among welders: “catching a bunny.” This means that the cornea of ​​the eye has been burned. We do not perceive infrared and ultraviolet rays with our eyes, but they have a very intense effect on the eyes. Moreover, negatively. Damaging the mucous membrane, retina and lens of the eye, causing a burn.

The main eye disease that occurs under the influence of light radiation from welding is electroophthalmia.

What other causes of eye damage from welding are there?

• Negligent attitude towards work. Often welders do not use special safety glasses, which are required to be used for safety reasons. Or the use of low-quality glasses purchased in order to save money;
• Smoke effects on the mucous membranes of the eyes;
• Release of gases affecting the eyes;
• Foreign body getting into the eye. Most often, these are very small pieces of metal that stick into the cornea.

What are the symptoms of eye damage from welding?

Symptoms of eye damage from welding are very similar to the symptoms of many ophthalmological and even allergic diseases. However, it is clear that such symptoms occur immediately after welding work, which means that the influence of the spectrum of the welding arc is to blame.

1. Severe lacrimation;
2. Redness and swelling of the eyelids and eyeball;
3. Sharp cutting pain in the eye;
4. Sensation as if sand had been poured into the eyes;
5. Fear of light;
6. Tight closure of the eyelids as a result of spasm.

All symptoms, especially pain, begin to intensify after a few hours. This means that the burn was still received. If the pain does not intensify and gradually vision and eye condition return to normal, after about 1-3 days there will be no burn.

However, the profession of a welder requires frequent business trips, trips out of town and other places where it is not always possible to receive qualified assistance at any time of the day. And ordinary people who accidentally receive such a specific eye burn do not always have such opportunities. What can be done, what preparations should I use, are there any universal drops after welding?

Which drops after welding to choose

The choice of medicine is made based on the stage of the burn. Each stage has its own symptoms.

First stage

• Very severe itching;
• Redness of the whites of the eye, which can be regarded as minor. Characterized by a faint pink color;
• Burning;
• Cloudy iris.

During this period, the use of drops after welding is the most effective means for therapy and prevention of the development of the disease.

What medications will be needed:

1. Anesthetic drops after welding. They will help relieve all unpleasant symptoms: pain, itching, feeling of sand in the eyes and others;
2. Vasoconstrictor drops. They will relieve swelling and inflammation;
3. Antibacterial drops. They will prevent infection from developing and accelerate tissue regeneration.

Therapy is carried out for 2-3 days; if symptoms do not go away or worsen, you should urgently consult a doctor.

Second stage

• Erosion of the cornea of ​​the eye;
• The conjunctiva is covered with a film;
• Severe photophobia, resulting in spasms;
• Very strong sharp pain when moving the eyeballs.

At this stage, to treat an eye burn, it is possible to use the above types of drops.

There are also third and fourth stages. Self-treatment is not recommended. These are very difficult stages, at the fourth stage tissue necrosis is already possible and only surgical intervention will help here. At these stages, the use of any medications in the form of drops is practically useless.

Indications for use

Cyprlet is prescribed to patients with inflammation of the eyes and their appendages, which are caused by microorganisms sensitive to cyprofloxacin: all the phases of conjunctivitis, cornea ulcer, caused by bacteria, chronic inflammation of the lacrimal ducts, blepharitis, blefaroconojunctivitis, kerato -cyncetivitis, bacterial keratitis, chronic conjunctivitis, chronic irony Docyclite, meibomite and chronic dacryocystitis. Tsiprolet eye drops can also be used for certain types of chemotherapy.

Prescribed for the prevention and treatment of infections caused by surgical interventions, in the event of complications in ophthalmic surgery, as well as complications after eye injuries and in cases of foreign bodies entering the eye. Can be used as a prophylactic agent before surgical interventions.

Anesthetic drops for gas after welding

First of all, after eye damage as a result of exposure to welding, it is necessary to relieve the pain of the victim. This is also necessary in order to more accurately assess the condition of the affected eye.

The pain can be so severe that the victim cannot even open his eyes.

These are the most famous types of welding eye drops, recommended as a local anesthetic for pain relief.

Their action is based on the blockade of voltage-dependent Na channels, which prevents the formation of impulses in nerve endings and the conduction of impulses along nerve fibers.

They are used by instilling 1-2 drops into the conjunctival sac. Restrictions on use are described in the instructions for use of drops after welding.

They have a fairly short-term effect. Side effects include local allergic irritation.

Contraindication is the period of waiting for a child and lactation, childhood.

Features of drug interactions

It is possible to use drops in combination with other antimicrobial medications:

• Metronidazole;
• aminoglycosides;
• Clindamycin;
• beta-lactam antibiotics.

When the organs of vision are damaged by streptococci, the medication is used in combination with Ceftazidime and Azlocillin. If the causative agent of the disease is streptococcus, additional use of Vancomycin and Isoxazolepenicillin is indicated. Eye drops are incompatible with medications with a pH level of 3-4.

Vasoconstrictor drops

After pain relief, a drug is used that will effectively treat pathological symptoms: relieve swelling, remove redness and inflammation, relieve itching.

These drugs are based on adrenergic agonists that act on the receptors of the vascular walls. They cause the blood vessels to constrict, resulting in relief of the symptoms of the disease.

Vasoconstrictor eye drops are very effective, but they cannot be used for a long time. Otherwise, they will cause the opposite effect.

Eye drops after welding with a vasoconstrictor effect are used for no longer than 5 days. Otherwise, addiction to the drug develops and then the symptoms that needed to be eliminated intensify.

Contraindications

The drug is contraindicated in case of viral keratitis and in case of increased individual sensitivity to its individual components, as well as to drugs from the quinolone group. It is not recommended for use during pregnancy, lactation (breastfeeding) and children under 1 year of age.

For diseases accompanied by cerebrovascular accidents, convulsions and atherosclerosis, drops should be used with extreme caution.

Antibacterial drops

If you receive a burn as a result of exposure to welding, then most likely inflammation has begun. This means the use of antibiotics will be required. But they must be in shape. Which will allow you to apply them topically, directly to the affected area.

The most famous drops with an antibacterial effect:

1. Tobrex;
2. Oftaquix;
3. Gentamicin;
4. Dexamethasone;
5. Taufon or Taurine.

Method of application: by introducing drops onto the conjunctival sac. The dose of use always depends on the severity of the condition, but the usual dosage is:

• For infections with moderate symptoms, antibacterial eye drops after welding are used in the amount of 1-2 drops with an interval of 4 days;
• For infections with symptoms of high severity, it is recommended to reduce the interval of drug administration - 1-2 drops every hour;
• Antibacterial drops can be used for a course of no more than 2 weeks.

Contraindications for use:

1. Intolerance to components;
2. Infancy (less than 1 year);
3. Severe kidney pathologies;
4. Pregnancy and breastfeeding;
5. Myasthenia;
6. Acoustic neuritis.

Important: long-term use of antibacterial eye medications beyond 2 weeks can lead to fungal or secondary bacterial infection.

• Reaction to light in the form of a spasm;
• lacrimation;
• Burning and itching;
• Development of bleeding of mucous membranes;
• Hallucinations.

pharmachologic effect

Drops have a strong bacteriostatic effect on the body. Thus, the production of DNA gyrase in bacterial molecules stops, which disrupts the process of gene reading in microbes and stops their division and growth. Active morphological changes occur in the membrane membrane of bacteria, after which they rapidly die.

The greatest effect of Tsiprolet is manifested in bacteria of the gram-negative group, and acts both during their growth and during dormancy. Impact on gram-negative bacteria is possible only at the reproduction stage.

The effective action of Tsiprolet drops is shown for diseases that are provoked by bacteria such as Helicobacter, Salmonella, Morganella, Shigella, Streptococcus, Proteus, Staphylococcus, Pneumococcus, Enterobacter, as well as Legionella, Listeria, Chlamydia, Mycobacteria and Corynebacteria.

Most staphylococci are resistant to ciprofloxacin. Sreptococcus pneumoniae, Micobacterium avium and Enterococcus faecalis have moderate resistance. To suppress them, it is necessary to increase the amount of the drug.

Resistant microorganisms: Bacteroides fragilis, Pseudomonas cepacia, Nocardia asteroides, Pseudomonas maltophillia, Clostridium difficile, Ureaplasma urealyticum. The product is not effective if used to combat fungi and Treponema pallidum. Resistance to the drug appears slowly and gradually.

The average concentration of ciprofloxacin in plasma after use is less than 2.5 ng/ml. The substance is excreted by the kidneys: 50.0% unchanged, no more than 10.0% in the form of metabolites, and approximately 15.0% is excreted through the gastrointestinal tract. During lactation, the substance is excreted in breast milk.

With the use of Ciprofloxacin, resistance to other antimicrobial drugs does not appear.

Eye drops after welding for quick regeneration

If the above complex treatment relieves the symptoms of an eye burn after welding, you need to use drugs that ensure the regeneration of injured tissue.

You can use various products in small courses so that they are not addictive and help restore your eyes faster.

According to ophthalmologists, the use of the following medications is recommended:

1. Emoxipin. The main direction of action is to help in the resorption of hemorrhages, tissue regeneration, strengthening of blood vessels;
2. Derinat. These eye drops after welding help solve the main problem of the burn - restore the gas mucosa and prevent the formation of scars;
3. Vitasik. General action drops have an effect on the mucous membrane and restore nerve endings.

During use, it is important to adhere to the recommendations and dosages that are contained in the instructions for using eye drops after welding.

What not to do if you have an eye injury after welding.

• No need to scratch your eyes. Or trying to get sand that you feel in your eye. It is not there, it is a symptom of inflammation and mechanical impact will increase the pain;
• Do not wash the injured eye with water. The weld burn does not require cooling. There are erosions on the mucous membrane and trace elements contained in water will only increase inflammation;
• In the acute stage of a burn, you cannot use well-known folk remedies: tea leaves, honey, aloe and others. They will only bring additional inflammation, allergic reactions and other undesirable consequences. It is generally better not to use such methods. There are a huge number of specialized eye medications on the pharmacy market;
• You cannot independently prescribe treatment and dosage of eye drops after welding. The best treatment will be prescribed by your doctor. Drops can be used urgently.

special instructions

If the doctor has prescribed two or more types of eye drops for the child, then an interval of 10–15 minutes must be observed between instillations.

To store drops, use a place protected from sunlight and out of reach of children. The storage temperature of the medicine should not exceed 25 ͦC.

Before instillation, you must wash your hands well. When putting drops in a child’s eyes, you need to make sure that the tip of the dropper does not touch the patient’s eyelids or eyes.

If the child uses contact lenses, they must be removed during treatment. The components contained in the medicinal solution can damage the lenses and impair their transparency.